Thursday, 13 April 2017

Magnetic micro-particle immune separation combined with enzyme linked immunosorbent assay for quick detection of Salmonella typhimurium in raw eggs

Magnetic micro-particle immune separation

An immunomagnetic separation (IMS) method was developed for separating Salmonella typhimurium bacteria from large-volume samples of raw eggs.

An egg was homogenized with a blender. The homogenized egg material was diluted with DI water to make a 200 mL sample mixture. Anti-Salmonella typhimurium antibody coated magnetic micro particles (MMP) were used to trap the Salmonella bacteria in the sample mixture.

The Salmonella-trapped MMP were separated from the egg sample matrices by using a large magnet. An enzyme-linked immunosorbent assay method was adopted and revised for detecting the bacteria trapped onto the MMP.

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